Pharmacology Practice Questions 2

  1. Which of the following is the antidote for benzodiazepine toxicity?
  1. Flumazenil
  2. Methylene blue
  3. Deferoxamine
  4. Alkalinize urine
Show Answer
The correct answer is A!

Flumazenil is a competitive GABA receptor antagonist that reverses benzodiazepine sedation or overdose.

 

  1. Which of the following is the antidote for lead poisoning?
  1. Naloxone
  2. Nitrite
  3. Calcium EDTA (CaEDTA)
  4. Dialysis
Show Answer
The correct answer is C!

Calcium EDTA chelates lead, forming a complex excreted in urine; dimercaprol and succimer may also be used.

 

  1. What is the primary site of activity for the anticoagulant warfarin?
  1. Kidney
  2. Liver
  3. Blood
  4. Heart
Show Answer
The correct answer is B!

Warfarin inhibits vitamin K epoxide reductase in the liver, reducing synthesis of clotting factors II, VII, IX, and X.

 

  1. Lansoprazole is not used for which of the following conditions?
  1. Gastritis
  2. Peptic ulcers
  3. Zollinger–Ellison syndrome
  4. Thalamus hypertrophy
Show Answer
The correct answer is D!

Lansoprazole, a proton pump inhibitor, treats acid-related disorders but has no neurological use.

 

  1. Which drug is associated with the adverse reaction known as cinchonism?
  1. Valproic acid
  2. Quinidine
  3. Isoniazid
  4. Ethosuximide
Show Answer
The correct answer is B!

Cinchonism (tinnitus, headache, dizziness, and blurred vision) occurs with quinidine and quinine toxicity.

 

  1. Which drug is commonly associated with the adverse effect of hepatitis?
  1. Valproic acid
  2. Quinidine
  3. Isoniazid
  4. Ethosuximide
Show Answer
The correct answer is C!

Isoniazid can cause hepatotoxicity, especially in slow acetylators or patients consuming alcohol.

 

  1. Which drug is associated with Stevens–Johnson syndrome?
  1. Valproic acid
  2. Quinidine
  3. Isoniazid
  4. Ethosuximide
Show Answer
The correct answer is D!

Ethosuximide and certain sulfa drugs are known triggers of Stevens–Johnson syndrome, a severe skin reaction.

 

  1. Which drug class is associated with tendon dysfunction and rupture?
  1. Digitalis
  2. Niacin
  3. Tetracyclines
  4. Fluoroquinolones
Show Answer
The correct answer is D!

Fluoroquinolones may cause tendonitis or Achilles tendon rupture, especially in older adults or corticosteroid users.

 

  1. A drug ending in the suffix -pril is considered a(n):
  1. Histamine antagonist
  2. ACE inhibitor
  3. Antifungal
  4. Beta agonist
Show Answer
The correct answer is B!

ACE inhibitors (like lisinopril and enalapril) block angiotensin-converting enzyme to lower blood pressure.

 

  1. A drug ending in the suffix -azole is considered a(n):
  1. Histamine antagonist
  2. ACE inhibitor
  3. Antifungal
  4. Beta agonist
Show Answer
The correct answer is C!

-azole drugs (e.g., fluconazole, ketoconazole) inhibit ergosterol synthesis in fungal cell membranes.

 

  1. A drug ending in the suffix -tidine is considered a(n):
  1. Antidepressant
  2. Protease inhibitor
  3. Beta antagonist
  4. H2 receptor antagonist
Show Answer
The correct answer is D!

-tidine drugs (e.g., ranitidine, famotidine) block H₂ receptors, decreasing stomach acid secretion.

 

  1. A drug ending in the suffix -navir is considered a(n):
  1. Antidepressant
  2. Protease inhibitor
  3. Beta antagonist
  4. H2 receptor antagonist
Show Answer
The correct answer is B!

-navir drugs (e.g., ritonavir, indinavir) are HIV protease inhibitors that block viral protein maturation.

 

  1. Which drug is associated with extreme photosensitivity?
  1. Digitalis
  2. Niacin
  3. Tetracycline
  4. Fluoroquinolones
Show Answer
The correct answer is C!

Tetracyclines cause severe sun sensitivity; patients should avoid direct sunlight and tanning beds.

 

  1. Which of the following is NOT associated with prednisone toxicity?
  1. Cataracts
  2. Hypotension
  3. Psychosis
  4. Acne
Show Answer
The correct answer is B!

Prednisone typically causes hypertension, not hypotension, along with weight gain, acne, and mood changes.

 

  1. Which of the following is NOT related to atenolol toxicity?
  1. Congestive heart failure (CHF)
  2. Tachycardia
  3. AV block
  4. Sedation/fatigue
Show Answer
The correct answer is B!

Atenolol, a beta blocker, slows heart rate—bradycardia, not tachycardia, is typical.

 

  1. Which of the following is a Class IA sodium channel blocker?
  1. Mexiletine
  2. Amiodarone
  3. Quinidine
  4. Procainamide
Show Answer
The correct answer is C!

Class IA antiarrhythmics (quinidine, procainamide, disopyramide) moderately block Na⁺ channels and prolong repolarization.

 

  1. Which of the following is also classified as a Class IA sodium channel blocker?
  1. Propafenone
  2. Disopyramide
  3. Amiodarone
  4. Quinidine
Show Answer
The correct answer is B!

Disopyramide is a Class IA sodium channel blocker, sharing properties with quinidine and procainamide.

 

  1. Potassium-sparing diuretics primarily act on which part of the nephron?
  1. Proximal convoluted tubule
  2. Loop of Henle
  3. Collecting duct
  4. Distal convoluted tubule
Show Answer
The correct answer is C!

Amiloride, triamterene, spironolactone, and eplerenone act on the collecting duct to inhibit Na⁺ reabsorption and prevent K⁺ loss.

 

  1. Which of the following is NOT a common adverse effect of nitroglycerin?
  1. Headache
  2. Tachycardia
  3. Dizziness
  4. Projectile vomiting
Show Answer
The correct answer is D!

Nitroglycerin causes headache, flushing, hypotension, and reflex tachycardia—but not projectile vomiting.

 

  1. Which of the following is NOT associated with ibuprofen toxicity?
  1. Nausea
  2. Renal dysfunction
  3. Anemia
  4. Muscle wasting
Show Answer
The correct answer is D!

Ibuprofen toxicity can cause GI upset, kidney injury, and rarely anemia due to GI bleeding. It does not cause muscle wasting; that is associated with prolonged steroid use or systemic disease.