- Which of the following conditions correlates with the following information:
- High pH
- High HCO3–
- High BE
- Normal pCO2
- Respiratory alkalosis
- Respiratory acidosis
- Metabolic acidosis
- Metabolic alkalosis
This is primary metabolic alkalosis without evident respiratory compensation yet. Base excess (BE) >+3 mEq/L supports a metabolic alkalosis.
- Which oxygen delivery device delivers the most precise, titratable FiO2, making it preferred when controlled oxygen delivery is needed?
- Nasal cannula
- Simple face mask
- Venturi mask
- Nonrebreather mask
The venturi mask uses jet entrainment with interchangeable ports to deliver a fixed, precise FiO2 (commonly 24–50%). This tight control is ideal when you must avoid excessive oxygen.
- Which lung volume CANNOT be measured directly by simple spirometry?
- Residual volume (RV)
- Tidal volume (TV)
- Vital capacity (VC)
- Inspiratory capacity (IC)
Simple spirometry records air that moves in and out of the lungs. It cannot capture the air that remains after maximal exhalation. Therefore, residual volume (RV) is not directly measurable by spirometry.
- Which of the following corresponds with a negative TB test?
- 0-4 mm induration at 48 hours
- 0-5 mm induration at 48 hours
- 0-6 mm induration at 48 hours
- 0-7 mm induration at 48 hours
TST is read at 48–72 h. In people without TB risk factors, <5 mm is considered negative.
Thresholds (≥5, ≥10, ≥15 mm) depend on risk category. Hence, 0–4 mm is the negative range in this context.
- Which of the following is the most common type of lung cancer?
- NSCLC
- SCLC
- Lung sarcoma
- Lung lymphoma
Non–small cell lung cancer (~85% of cases) is more common than small cell. NSCLC includes adenocarcinoma, squamous cell, and large cell subtypes.
- What cell type secretes surfactant?
- Plasma cell
- Type I alveolar cell
- Type II alveolar cell
- Type III alveolar cell
Type II pneumocytes secrete pulmonary surfactant, reducing alveolar surface tension and preventing collapse. Type I cells mediate gas exchange, and “Type III” isn’t a standard pneumocyte category.
- Which of the following is most characteristic of obstruction of the trachea or larynx?
- Rhonchi
- Stridor
- Wheezes
- Vesicular
Stridor is a high-pitched inspiratory sound from upper airway (larynx/trachea) obstruction. Wheezes are lower-airway, rhonchi suggest secretions in larger airways, and vesicular is a normal breath sound.
← Click to hear what stridor sounds like!
- Which of the following is a normal range for pCO2?
- 20-40 mm Hg
- 25-30 mm Hg
- 30-40 mm Hg
- 35-45 mm Hg
Normal arterial pCO2 is 35–45 mm Hg. Values like 20–40, 25–30, or 30–40 mm Hg are below normal (hypocapnia ranges).
- Which of the following is a normal range for HCO3?
- 15-30 mEq/L
- 20-35 mEq/L
- 22-26 mEq/L
- 24-29 mEq/L
Normal serum bicarbonate is 22–26 mEq/L. This value guides metabolic contributions to acid–base status (also reflected in BE).
- Pneumocystis jirovecii pneumonia is treated with which of the following when TMP-SMX is contraindicated?
- Pentamidine
- Allopurinol
- Lorazepam
- Chlorpropamide
TMP-SMX is first-line for P. jirovecii pneumonia. Pentamidine (IV or inhaled) is a recognized alternative when TMP-SMX is contraindicated or not tolerated.
- Which of the following is NOT a typical complication of COPD?
- Pneumonia
- Right-sided heart failure
- Headaches
- Cor pulmonale
COPD commonly leads to cor pulmonale and right-sided heart failure, and increases risk of pneumonia. Headaches can occur but are symptoms, not a classic complication like the others.
- Which of the following is NOT considered a COPD-related disease?
- Bronchiectasis
- Bronchial asthma
- Chronic bronchitis
- Bronchial hypotension
COPD encompasses chronic bronchitis and emphysema. Asthma and bronchiectasis are obstructive diseases that may coexist but are distinct. “Bronchial hypotension” isn’t a recognized disease entity.
- Which of the following is a bronchospasm of the bronchial walls?
- Wheeze
- Rhonchus
- Stridor
- Pleural rub
A wheeze indicates bronchospasm in narrowed airways (musical, high-pitched). Rhonchi are low-pitched from secretions, stridor is upper-airway, and pleural rub is a grating sound from inflamed pleura.
← Click to hear what a wheeze sounds like!
- Which of the following is considered an expectorant?
- Dextromethorphan
- Guaifenesin
- Benzonatate
- Codeine
Guaifenesin is an expectorant that thins mucus to aid clearance. Dextromethorphan, benzonatate, and codeine are antitussives (cough suppressants).
- Which of the following is considered a bronchodilator?
- Acetylcysteine
- Guaifenesin
- Budesonide
- Epinephrine HCl
Epinephrine is a sympathomimetic bronchodilator (α/β agonist) that relaxes bronchial smooth muscle.
Acetylcysteine is a mucolytic, guaifenesin an expectorant, and budesonide an inhaled corticosteroid (anti-inflammatory, not a bronchodilator).
- Which of the following is considered a xanthine?
- Salmeterol
- Ipratropium bromide
- Theophylline
- Budesonide
Theophylline is a xanthine derivative bronchodilator. Salmeterol (LABA), ipratropium (antimuscarinic), and budesonide (ICS) are not xanthines.
- Which of the following is considered a mucolytic?
- Acetylcysteine
- Dextromethorphan
- Phenylephrine
- Loratadine
Acetylcysteine breaks disulfide bonds in mucus → mucolysis. Dextromethorphan, phenylephrine, loratadine are not mucolytics.
- Which of the following is the volume of air that can be inhaled following exhalation of tidal volume?
- Expiratory reserve volume
- Inspiratory capacity
- Inspiratory reserve volume
- Vital capacity
Inspiratory capacity is the volume that can be inhaled after a normal exhalation of tidal volume (\(\text{IC} = \text{TV} + \text{IRV}\)). IRV alone is the extra volume after a normal inspiration, not after exhalation.
- Which of the following is the maximum volume of air that can be exhaled after taking the deepest breath possible?
- Expiratory reserve volume
- Inspiratory capacity
- Inspiratory reserve volume
- Vital capacity
Vital capacity is the maximum exhaled volume after the deepest possible inhalation (\(\text{VC} = \text{IRV} + \text{TV} + \text{ERV}\)).
- The respiratory center is located in the ______ and ______.
- Midbrain and pons
- Pons and medulla oblongata
- Midbrain and medulla oblongata
- Pons and hypothalamus
The respiratory center comprises medullary and pontine centers in the medulla oblongata and pons, coordinating rate and depth of breathing.